Allergen Details:
| Allergen name: | Jug r 5 |
|---|---|
| Lineage: |
Source: Plantae Magnoliopsida Order: Fagales Species: Juglans regia (English walnut) |
| Biochemical name: | PR-10 |
| MW(SDS-PAGE): | 20 kDa |
| Allergenicity: | Based on case history of allergy to English walnut, for those with + IgE binding by ImmunoCAP to recombinant E. coli produced protein (Walnut specific Immunocap to PR-10) and SPT (used Alyostal, Stallergens). Food challenges with DBPCFC 9 positive, open food challenge, 5 positive were both done using raw walnut from a local food market. seems to be due to primary sensitization to birch pollen allergy. But they have evidence this PR-10 is expressed in the nut and it was able to inhibit bindign to a 20 kDa IgE binding band in walnut extract. |
| Food allergen: | Yes |
| Date Created: | 2016-06-26 12:00:00 |
| Last Updated: | 2016-10-11 13:13:00 |
| Submitter Info: | |
| Name: | Andrea Wangorsch |
| Institution: | Paul Ehrlich Institute |
| City: | Langen, Germany |
| Email: | andrea.wangorsch@pei.de |
| Date: | 2016-04-19 |
Comments
| Isoallergen and variants | GenBank Nucleotide | GenBank Protein | UniProt | PDB |
|---|---|---|---|---|
| Jug r 5.0101 | KX034087.1 | APD76154.1 |