Allergen Details:
| Allergen name: | Der p 13 |
|---|---|
| Lineage: |
Source: Animalia Arthropoda Order: Astigmata Species: Dermatophagoides pteronyssinus (European house dust mite) |
| Biochemical name: | Cytosolic Fatty Acid Binding Protein |
| MW(SDS-PAGE): | 15 kDa |
| Allergenicity: | 224 "HDM-allergic" subjects living in Thailand, with rhinitis or asthma were tested for IgE binding to Dermatophagoides pteronyssinus ImmunoCAP and were class 3 or higher. Serum IgE binding to recombinant Der p 13 produced in Picchia, were tested by ELISA with 15 of 224 positive. |
| Food allergen: | No |
| Date Created: | 2016-03-15 12:00:00 |
| Last Updated: | 2016-10-11 12:59:46 |
| Submitter Info: | |
| Name: | Alain P.A. Jacquet |
| Institution: | Chulalongkorn University, Dept. of Medicine |
| City: | Bangkok, Thailand |
| Email: | alain.j@chula.ac.th |
| Date: | 2016-03-09 |
Comments
| Isoallergen and variants | GenBank Nucleotide | GenBank Protein | UniProt | PDB |
|---|---|---|---|---|
| Der p 13.0101 | HM560018 | ADK92390 | E0A8N8 |
Sequences were originally from Heinrich,T., Smith,W.-A. and Thomas,W.R. in 2010. A. Jacquet indicates the submitter constructed a rDNA in Picchia pastoris, expressed and used the protein in tests. They indicate 90% sequence coverage by MSMS.