Allergen Details:
| Allergen name: | Per a 1 |
|---|---|
| Lineage: |
Source: Animalia Arthropoda Order: Blattodea Species: Periplaneta americana (American cockroach) |
| Obsolete name: | Cr-PII |
| MW(SDS-PAGE): | 45 |
| Allergenicity: | - Of 35 allergic patients, 22 had a positive skin test to CR-extract and Per a 1. Of these 22 patients, 12 (54.4%) showed a positive skin reaction to rPer a 1. IgE Ab binding to rPer a 1 was demonstrated in ELISA. - Amino acid sequences 78LIRALFGL85 and 267IRSWFGLP1274 of the American cockroach Per a 1.0104 allergen were involved in IgE binding, as measured by ELISA. 80%-100% of the sera tested showed IgE binding to these peptides: medline 22302513. |
| Allergenicity ref.: | 10221434 |
| Food allergen: | No |
| Date Created: | 2003-05-16 12:00:00 |
| Last Updated: | 2010-04-29 16:57:55 |
| Submitter Info: | |
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Comments
| Isoallergen and variants | GenBank Nucleotide | GenBank Protein | UniProt | PDB |
|---|---|---|---|---|
| Per a 1.0101 | AF072222 | AAD13533 | Q9TZR6 | |
| Per a 1.0102 | U78970 | AAC34312 | O18535 | |
| Per a 1.0103 | U69957 | AAB82404 | O18530 | |
| Per a 1.0104 | U69261 | AAC34737 | O18528 | |
| Per a 1.0201 | U69260 | AAC34736 | O18527 |