Allergen Details:
Allergen name: | Hev b 1 |
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Lineage: |
Source: Plantae Magnoliopsida Order: Malpighiales Species: Hevea brasiliensis (Para rubber tree (latex)) |
Biochemical name: | Rubber elongation factor |
MW(SDS-PAGE): | 14 |
Allergenicity: | - Of 140 patients with spina bifida (SB), 81% had IgE against Hev b 1, as measured by EAST. Of 105 health care workers allergic to latex, 52% had Hev b 1 specific IgE. - None of the 20 latex-allergic patients tested showed IgE binding to nHev b 1 or rHev b 1 on immunoblot. However, both allergens were recognized by 2 serumpools of patients with SB: medline 96426247. - Hev b 1 was recognized by 18 out of 21 patients with SB, but only by 2 of 14 patients with latex-allergy: medline 94004042 |
Allergenicity ref.: | 9389300 |
Food allergen: | No |
Date Created: | 2003-07-03 12:00:00 |
Last Updated: | 2010-04-29 16:57:55 |
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Comments
Isoallergen and variants | GenBank Nucleotide | GenBank Protein | UniProt | PDB |
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Hev b 1.0101 | X56535 | CAA39880 | P15252 |