Allergen Details:
Allergen name: | Blo t 2 |
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Lineage: |
Source: Animalia Arthropoda Order: Astigmata Species: Blomia tropicalis (Storage mite) |
Food allergen: | No |
Date Created: | 2006-11-05 12:00:00 |
Last Updated: | 2010-04-29 16:57:55 |
Submitter Info: | |
Name: | |
Institution: | |
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Email: | |
Date: |
Comments
Isoallergen and variants | GenBank Nucleotide | GenBank Protein | UniProt | PDB |
---|---|---|---|---|
Blo t 2.0101 | AY288141 | AAQ73483 | Q1M2P1 | |
Blo t 2.0102 | AY288140 | AAQ73482 | Q1M2P2 | |
Blo t 2.0103 | AY288139 | AAQ73481 | Q1M2P3 |
There is little published evidence of allergy or IgE binding to the sequences previously recognized as Blo t 2. The submitters did not provide information for allergy to these proteins. However the 2011 publication by Kidon et al., indicates there were a number of subjects with IgE binding by direct ELISA with IgE to a slightly different sequence than any of the listed isoforms Blo t 2. That sequence is between 88% and 95% identical to the three indicated isoforms in IUIS. The reference is PMID 21332797. 26 Oct 2014 REG